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SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9.5
USERS' SCORE
Good
Based on 28 Reviews
8.1
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Calcium (elemental) (from 2,775 mg complex of Calcium Carbonate, Calcium Citrate, Calcium Ascorbate)
1 g (1,000 mg)
77%
Magnesium (elemental) (from 928 mg complex of Magnesium Oxide, Magnesium Citrate, Magnesium Ascorbate)
500 mg
119%
Top Medical Research Studies
9.5
Calcium's role in RA treatment
Hydrolysis of 2D Nanosheets Reverses Rheumatoid Arthritis Through Anti-Inflammation and Osteogenesis.
Focus on calcium's therapeutic potential
We investigated how calcium, specifically in the form of two-dimensional layered calcium disilicide nanoparticles (CSNs), can play a role in treating rheumatoid arthritis (RA). Unlike typical RA treatments that primarily focus on reducing inflammation, we observed that CSNs have multifunctional properties that can address the inflammatory aspect while also promoting bone health and repair.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Read More
Most Useful Reviews
9.5
Strong nails improvement
Very high-quality calcium combined with magnesium. I’ve been using NowFoods products for a while, and this calcium to magnesium blend did not disappoint. My nails, which weren't strong naturally, became noticeably stronger and shinier. I also had issues with tooth enamel, but now I don’t feel sensitivity to acids or temperature. Magnesium has helped me manage stress, making me calmer. I confidently recommend this supplement for strengthening nails, teeth, and supporting bone health and the nervous system.
Read More
9.5
Improved joint health
This calcium has been wonderful! I started taking it regularly six months ago on my doctor’s advice, primarily for my rheumatoid arthritis. Among many brands I've tried, this one has no side effects and is well absorbed. My nails no longer separate, and I no longer have stomach aches. I've also been sleeping better, which I attribute to magnesium. This is now a regular purchase for my family and me, as I believe daily calcium is essential for health.
Read More
9.5
Joint pain relief
This is my first product from iHerb. I noted various symptoms like joint pain and fatigue after childbirth due to a calcium and magnesium deficiency. I have been taking it for over ten days, and I feel none of those symptoms now! I am quite pleased with the results.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9.5
9.5
Calcium's role in RA treatment
Hydrolysis of 2D Nanosheets Reverses Rheumatoid Arthritis Through Anti-Inflammation and Osteogenesis.
Focus on calcium's therapeutic potential
We investigated how calcium, specifically in the form of two-dimensional layered calcium disilicide nanoparticles (CSNs), can play a role in treating rheumatoid arthritis (RA). Unlike typical RA treatments that primarily focus on reducing inflammation, we observed that CSNs have multifunctional properties that can address the inflammatory aspect while also promoting bone health and repair.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Read More
User Reviews
USERS' SCORE
Good
Based on 28 Reviews
8.1
10
Cramps alleviated
I waited a year to use this supplement and started after my daughter was born. Now, after four months, I can say it's effective. I no longer have leg cramps during sleep or exercise. I feel calm despite being home with my child. I also think it's helped maintain my teeth and nails in good condition.
Read More
9.5
Strong nails improvement
Very high-quality calcium combined with magnesium. I’ve been using NowFoods products for a while, and this calcium to magnesium blend did not disappoint. My nails, which weren't strong naturally, became noticeably stronger and shinier. I also had issues with tooth enamel, but now I don’t feel sensitivity to acids or temperature. Magnesium has helped me manage stress, making me calmer. I confidently recommend this supplement for strengthening nails, teeth, and supporting bone health and the nervous system.
Read More
9.5
Improved joint health
This calcium has been wonderful! I started taking it regularly six months ago on my doctor’s advice, primarily for my rheumatoid arthritis. Among many brands I've tried, this one has no side effects and is well absorbed. My nails no longer separate, and I no longer have stomach aches. I've also been sleeping better, which I attribute to magnesium. This is now a regular purchase for my family and me, as I believe daily calcium is essential for health.
Read More
9.5
Joint pain relief
This is my first product from iHerb. I noted various symptoms like joint pain and fatigue after childbirth due to a calcium and magnesium deficiency. I have been taking it for over ten days, and I feel none of those symptoms now! I am quite pleased with the results.
9.5
Nervous system improvement
This is my first order from iHerb. The large packaging impressed me, as I usually overpay for smaller sizes locally. I've been taking these vitamins for a month, and I’ve noticed a benefit in strengthening my bones and improving my nervous system. I felt an improvement after about three weeks and wish to continue taking them.
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